The Binding of Isaac: Rebirth

Official controller support: full

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Controller or Keyboard and Mouse?

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D956bc4013e234d687e01e910297bd80cde68345 medium
Honestly, it is debatable and dependant on the scenario for whether which is better, as certain weapons and items allow for mouse aiming (with config changes) while analog stick (and maybe other items) allow for 360 degree analog input being meaningful.
5b803c4b551ece328280f118440147f4edbf6086 medium
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